Multifunctional chitosan modified Gd2O3:Yb3+,Er3+@nSiO2@mSiO2 core/shell nanoparticles for pH responsive drug delivery and bioimaging

pH-Responsive nanoparticles for drug delivery.

First-generation nanoparticles (NPs) have been clinically translated as pharmaceutical drug delivery carriers for their ability to improve on drug tolerability, circulation half-life, and efficacy. Toward the development of the next-generation NPs, researchers have designed novel multifunctional platforms for sustained release, molecular targeting, and environmental responsiveness. This review ...

ph-responsive and macrophage evading low molecular weight chitosan coated nanoparticles for tumor-specific drug delivery

Supporting Information Multifunctional Polymer-Capped Mesoporous Silica Nanoparticles for pH-Responsive Targeted Drug Delivery

1Department of Chemistry, Nanosystems Initiative Munich (NIM) and Center for Nano Science (CeNS), University of Munich (LMU), Butenandtstr. 11 (E), 81377 Munich, Germany 2Department of Pharmacy, Pharmaceutical Biotechnology, Nanosystems Initiative Munich (NIM) and Center for Nano Science (CeNS), University of Munich (LMU), Butenandtstr. 5-13, 81377 Munich, Germany # authors contributed equally ...

Multifunctional polymer-capped mesoporous silica nanoparticles for pH-responsive targeted drug delivery.

A highly stable modular platform, based on the sequential covalent attachment of different functionalities to the surface of core-shell mesoporous silica nanoparticles (MSNs) for targeted drug delivery is presented. A reversible pH-responsive cap system based on covalently attached poly(2-vinylpyridine) (PVP) was developed as drug release mechanism. Our platform offers (i) tuneable interactions...

pH-Responsive Mesoporous Silica and Carbon Nanoparticles for Drug Delivery

The application of nanotechnology to medicine constitutes a major field of research nowadays. In particular, the use of mesoporous silica and carbon nanoparticles has attracted the attention of numerous researchers due to their unique properties, especially when applied to cancer treatment. Many strategies based on stimuli-responsive nanocarriers have been developed to control the drug release ...